Nanobiotechnology BY Neelima Sharma,WCC CHENNAI,email@example.com
Published on: Mar 3, 2016
Transcripts - Nanobiotechnology BY Neelima Sharma,WCC CHENNAI,firstname.lastname@example.org
NANOSCIENCE• Nanosciene is the Science of Tiny Things
Nano:A prefix that means very, very, small. • • The word nano is from the Greek word The word nano is from the Greek word ‘Nanos’ meaning Dwarf. ItItis aaprefix used to ‘Nanos’ meaning Dwarf. is prefix used to describe "one billionth" of something, or describe "one billionth" of something, or 0.000000001 0.000000001..
NANOSCALE 0.7 nm 22 cm 12,756 Km1.27 × 107 m 0.22 m 0.7 × 10-9 m 10 millions times 1 billion times smaller smaller
NANOTECHNOLOGY• Nanotechnology, shortened to "nanotech", is the study of the controlling of matter on an atomic and molecular scale. Generally nanotechnology deals with structures sized 100 nanometres or smaller in at least one dimension, and involves developing materials or devices within that size.
• NANOTECHNOLOGY+BIOTECHNOLOGY NANOBIOTECHNOLOGY
WHAT IS NANOBIOTECHNOLOGY Semiconducting metal junctionAn engineered DNA pRNA tiny motor formed by two carbon nanotubesstrandNanobiotechnology is the creation of functional materials, devices andsystems, through the understanding and control of matter atdimensions in the nanometer scale length (1-100 nm), where newfunctionalities and properties of matter are observed and harnessedfor a broad range of applications
OBJECTIVE OF NANOBIOTECHNOLOGY• The imaging of native biomolecules, biological membranes, and tissues.• Use of cantilever array sensors.• Application of nanophotonics for manipulating molecular processes in living cells.
Application of Nanobiotechnology• Biological imaging for medical diagnostics.• Advanced drug delivery systems.• Biosensors for airborne chemicals or other toxins.• Regenerative medicine:• More durable, rejection- resistant artificial tissues and organs.
NANOBIOTECHNOLOGY IN CANCER−To develop cure for traditionally incurable diseases (e.g. cancer) through the utilization of nanobiotechnology.−To provide more effective cure with fewer side effects by means of targeted drug delivery systems
• Thermal ablation of cancer cells − Nanoshells have metallic outer layer and silica core − Selectively attracted to cancer shells either through a phenomena called enhanced permeation retention or due to some molecules coated on the shells − The nanoshells are heated with an Thermal ablation of cancer cells assisted by nanoshells coated with metallic layer external energy source killing the and an external energy source – National Cancer cancer cells Institute
Nanobiotechnology helps in early diagnosis• Higher sensitivity: detection of early biomarkers• Non- invasive and painless diagnostic techniques• Genetic testing for individual therapy selection
DRUG DELIVERY• Targeted drug delivery− Nanoparticles containing drugs are coated with targeting agents (e.g. conjugated antibodies)− The nanoparticles circulate through the blood vessels and reach the target cells− Drugs are released directly into the targeted cells
Regenerative Medicine• Biomimicking cell membranes• Polymers with programmable• conformation• Targeted Cell implantation• Control of implant rejections
CONCERNS OF NANOBIOTECHNOLOGY• Experts report smaller particles are more bioactive and toxic. Their ability to interact with other living systems increases because they can easily cross the skin, lung, and in some cases the blood/brain barriers. Once inside the body, there may be further biochemical reactions like the creation of free radicals that damage cells.