Nanotechnology v lv
Published on: Mar 3, 2016
Transcripts - Nanotechnology v lv
Manuel Del Valle Ortiz
RISE Program : Summer 2010
What is nanotechnology?
Tissue regeneration is actual full scale
project in nanotechnology that has not yet
reach its total development.
Biotechnology is also a main component in
In this research, tissue regeneration will be
exposed to many test on “nanotech” working
as a extracellular matrix and a scaffold
sending different messages to the cell. The
final result of this tests should be an
acceleration on tissue regeneration.
By making a correct design of a scaffold
for tissue regeneration we can
recapitulate extracellular matrix (ECM)
function in a temporally coordinated and
spatially organized structure which will
allowed us to accelerate the process for
To obtain a new class of hybrid materials,
capable of directly interacting with the cell.
To establish the necessary procedure to grow
skin tissue in the designed material.
Nanofabricated and microfabricated tissue
engineering scaffolds have the potential to
direct cell fate as well as to regulate
Synthetic polymeric nanofibers, obtained by
electrospinning, can be used to make a highly
porous non-woven structure comprising tiny
fibers where we can control cells growth.
Controlled growth factor delivery systems can
be used, in combination with techniques to
produce porous scaffolds, to provide
guidance in morphogenesis.
In the guiding of a cell though a tailor made
scaffold, the ability to elicit a specific
response to signal gradient is a key design
The appropriate attachment of the requisite
signal species to the scaffold help cell
guidance through the scaffold and all aspects
of cell response—adhesion and migration,
proliferation and phenotype choice—proceed
For scaffold materials, there must be the
correct balance between architectural
features notably porosity and physical
For this experiment I will be using tissue
Skin tissue cells will be purchased to grow
them in the scaffold material.
We will apply different growth factors to
control cell division.
This experiment is necessary to be repeated
many times before getting to any conclusion.
Many different results may occur during the
cell regeneration process.
Therefore I must keep track of any changes to
the tissue. This changes are to be compared
to other tissue culture cells in normal
If the experiment show some failure rate then
it must be reorganized and changes in
materials and procedure must be done.
If the experiment is successful then other
steps will be taken to use the tissue in
experimental animals and latter on humans.
This is an important experiment to
acknowledge the regenerative functions of a