Prevalence of Chronic Kidney Disease in HIV Infected Patients 2014
Life expectancy in HIV-infected patients has increased by 10 - 20 years in developed countries with the use of ART; many of these patients are now dying from the
complications of ESKD and other chronic diseases, rather than HIV infection.
Published on: Mar 4, 2016
Transcripts - Prevalence of Chronic Kidney Disease in HIV Infected Patients 2014
PREVALENCE OF CHRONIC KIDNEY DISEASE
IN HIV INFECTED PATIENTS 2014
DR JOSE LUIS RODRIGUEZ
HIV-associated CKD (HIV-CKD)
Studies from Africa have shown a variable prevalence of renal
disease in HIV, ranging from 6% to 45% :
(6% in SA, 38% in Nigeria, 26% in Cote d’Ivoire, 28% in
Tanzania, 25% in Kenya, 20 - 48.5% in Uganda, and 33.5% in
Zambia), depending on the populations studied and the criteria
for diagnosis of kidney disease. Part of this wide variation may
be ascribed to differences in study design, populations studied
and definitions used for CKD. Recent literature recommends
the CKD-EPI formula as the most reliable in calculating eGFR in
this patient population.
S Afr Med J 2015;105(4):320. DOI:10.7196/SAMJ.
Screening for CKD in HIV
• Statistics in the USA estimate the incidence of
HIVAN as 3.5 - 12%. If this were to be
extrapolated to SSA, where an estimated 22
million are infected with HIV, between 770 000
and 2.64 million people would be predicted to
have HIVAN. With the advent of wider access to
ART, the epidemiological pattern of HIVAN that
evolved in the USA over the last 14 years may
predict what will happen in SSA.
Ross MJ, Klotman PE. Recent progress in HIV-associated nephropathy. J Am Soc
ESKD due to HIV-CKD
Life expectancy in HIV-infected patients has
increased by 10 - 20 years in developed
countries with the use of ART; many of these
patients are now dying from the
complications of ESKD and other chronic
diseases, rather than HIV infection.
Currently, HIV-infected patients requiring
either hemodialysis or peritoneal dialysis, who
are stable on ART, are achieving survival rates
comparable with those of dialysis patients
without HIV infection. The choice of dialysis
modality does not impact on survival.
Kidney International (2004) 67, 2089–2100
1.-The country needs of a National Prevention
Program of CKD .
*Despite a lot of advancement in the fields of Medicine
, still there is not permanent cure for Kidney Failure.
2.-The Ministry of Health is concern about the
Namibian people affected with Chronic Renal
Failure, this is a challenger because is necessary
to developed a Dialysis National Program and a
Kidney Transplantation Program.