Nasal spary xylometazoline
Published on: Mar 3, 2016
Transcripts - Nasal spary xylometazoline
XylometazolineHydrochloride Nasal Spray/Drop
Composition Adult Composition….. Xylometazoline Hydrochloride IP 0.1%w/v Benzalkonium Chloride IP 0.01%w/v (As Preservative) An aqueous isotonic solution using Purified Water.. IP q.s• Pediatric composition……. Xylometazoline Hydrochloride IP 0.05 % w/v Benzalkonium Chloride IP 0.01% w/v (As Preservative) An aqueous isotonic solution using IP q.s Purified Water..
Xylometazoline (also known as xylomethazoline) is a drug which is used as a topical nasal decongestant. Itis applied directly into the nose, either as a spray or as drops Xylometazoline is marketed under many brand names with the typical adult solution strength being 0.1% w/v xylometazoline, and the dose for children under 12 being 0.05%
Mechanism of Action• The drug works by constricting the blood vessels in the nose. The vasoconstriction means that there is less pressure in the capillaries and less water can filter out, thus less discharge is made. (If the colour of the nasal passage is observed, it is visibly paler after dosage.)• Xylometazoline is an imidazole derivative which is designed to mimic the molecular shape of adrenaline. It binds to alpha-adrenergic receptors in the nasal mucosa.
Xylometazoline Nasal spray is used for:• Nasal congestion• Common cold• Sinusitis• Nasal allergies (allergic rhinitis)• Xylometazoline is used to help clear the stuffy, blocked up feeling in the nose and sinuses caused by colds and allergies such as hayfever.
Usage• One spray should be used in each nostril one to three times a day as necessary.• The spray can be used for up to a week. Storage Condition• Keep all medicines out of the reach and sight of children.• Store in a cool, dry place, away from direct heat and light.
Side effects• Irritation of the nose• Dryness inside the nose
Precautions• Do NOT use Xylometazoline spray if• If you are pregnant or breast-feeding.• If you have diabetes, high blood pressure,• If you have ever had an allergic reaction to this or to any other medicine.• If you are taking any other medicines, including those available to buy without a prescription. You must not use xylometazoline if you have taken a
Rates,Mrp and Packing• Rates 7.50/wc in 10ml for 0.1%• Mrp 40 to 55• Rates 7.25/wc in 10ml for 0.05%• Mrp 25 to 35• Expiry 2 years• Bottle oval shaped white HDPE.